Table 2. Assessment of the clinicopathological factors by the log-rank test.
Parameter | DFS (%) | p-value | DSS (%) | p-value | OS (%) | p-value |
Age (years) | 0.847 | 0.764 | 0.545 | |||
≤60 | 54 | 62 | 62 | |||
>60 | 52 | 59 | 52 | |||
Gender | 0.677 | 0.713 | 0.025* | |||
Male | 52 | 60 | 57 | |||
Female | 100 | 100 | 0 | |||
Smoking status | 0.384 | 0.248 | 0.403 | |||
None smoker | 71 | 75 | 70 | |||
Past smoker | 51 | 54 | 52 | |||
Current smoker | 45 | 45 | 45 | |||
Alcohol consumption | 0.170 | 0.151 | 0.278 | |||
None drinker | 66 | 72 | 66 | |||
Moderate drinker | 37 | 37 | 37 | |||
Heavy drinker | 43 | 55 | 52 | |||
Primary tumor site | 0.003* | 0.049* | 0.050* | |||
Pyriform sinus | 60 | 69 | 67 | |||
Posterior pharyngeal wall | 46 | 43 | 39 | |||
Postcricoid region | 0 | 0 | 0 | |||
T classification | 0.124 | 0.335 | 0.133 | |||
T1/T2 | 65 | 66 | 66 | |||
T3/T4 | 40 | 52 | 48 | |||
Cervical metastasis | 0.005* | 0.024* | 0.026 | |||
Yes | 40 | 52 | 48 | |||
No | 83 | 82 | 82 | |||
Postoperative irradiation | 0.082 | 0.153 | 0.168 | |||
Yes | 45 | 54 | 52 | |||
No | 72 | 72 | 66 | |||
Margin involvement | 0.201 | 0.344 | 0.503 | |||
Yes | 37 | 48 | 46 | |||
No | 60 | 65 | 60 | |||
Histologic differentiation | 0.986 | 0.633 | 0.535 | |||
Well | 57 | 65 | 65 | |||
Moderately | 45 | 57 | 46 | |||
Poorly | 39 | 42 | 42 | |||
Lymphovascular invasion | 0.279 | 0.470 | 0.420 | |||
Yes | 46 | 54 | 51 | |||
No | 66 | 68 | 68 | |||
Extracapsular spread | 0.001* | 0.003* | 0.004* | |||
Yes | 29 | 43 | 42 | |||
No | 76 | 77 | 74 | |||
High risk HPV status | 0.026* | 0.047* | 0.324 | |||
Positive | 100 | 100 | 83 | |||
Negative | 46 | 54 | 52 |
DFS, disease-free survival; DSS, disease-specific survival; OS, overall survival.
p<0.05.