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. 2013 Nov 11;8(11):e79030. doi: 10.1371/journal.pone.0079030

Table 3. Risk of Atrial Fibrillation among those with Orthostatic Hypotension as compared to those without by several sub-groups.

Strata Number (%of sample) HR 95% CI p value
Overall 12071 (100%) 1.4 (1.15,1.71)
Age<55 years 6384 (52.9) 1.44 (0.93,2.25) 0.74
Age ≥55 years 5687 (47.1) 1.51 (1.21,1.87)
Female 6647(55.1) 1.66 (1.27,2.18) 0.07
Male 5425 (44.9) 1.20 (0.89,1.16)
African American 3056 (25.3) 1.82 (1.20,2.70) 0.18
Caucasian 9015 (74.7) 1.32 (1.05,1.65)
Prevalent CHD 564 (4.7) 1.35 (0.74,2.49) 0.47
No CHD 11507 (95.3) 1.41 (1.15,1.75)
Diabetes 1116 (9.2) 1.34 (0.82,2.18) 0.29
No Diabetes 10955 (90.8) 1.43 (1.15,1.78)
Hypertension 4064 (33.7) 1.44 (1.12,1.85) 0.71
No hypertension 8007 (6.3) 1.33 (0.96,1.85)
Medication intake 4098 (34.0) 1.66 (1.26,2.19) 0.03
No medications intake 7973 (66.1) 1.08 (0.76,1.54)

Results from the Atherosclerosis Risk in Communities Study: 1987–89 through 2009.

CHD = Coronary Heart Disease, HF = Heart Failure, HR = Hazard Ratio.

p for interaction will be low if the relationship is different in the two strata of variable, and refers to p value for the term Orthostatic Hypotension*Strata variable in a model including both these variables and other potential confounders.

Medications refers to the drugs that have tendency to cause orthostatic hypotension including anti-hypertensive.