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. 2013 Nov 11;8(11):e79062. doi: 10.1371/journal.pone.0079062

Figure 4. High concentrations of GHB can induce an inward current that is completely abolished by the GABAB antagonist GCP 55845.

Figure 4

A1, Representative recording from a VB thalamic neuron showing the inward current induced by 3 mM GHB, and its blockade by CGP 55845 revealing no residual current. A2, Group results showing the current induced by GHB and its complete blockade by CGP 55845. B1, Representative recording from a dentate gyrus (DG) granule cells showing the inward current induced by 3 mM GHB, and its blockade by CGP 55845 revealing no residual current. B2, Group results showing the current induced by GHB and its complete blockade by CGP 55845. C1, Representative recording from a striatal medium spiny neuron (MSN) the complete lack of response to 3 mM GHB and CGP 5584. C2, Group results showing the lack of effect of GHB or CGP 55845.