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. 2013 Aug;49(2):269–278. doi: 10.1165/rcmb.2012-0291OC

Figure 4.

Figure 4.

Age-dependent alterations in cellular antioxidant concentrations in WT and mif−/− mice. Nonradiated mif−/− mice demonstrated an age-dependent decrease of antioxidant concentrations in BAL fluid compared with WT age-matched control mice, whereas nonradiated 16-month-old mif−/− mice exhibited significantly reduced antioxidant concentrations in BAL fluid compared with age-matched WT mice. Radiation resulted in significantly reduced concentrations of antioxidants in the BAL fluid of both WT and mif−/− mice after 6 weeks, compared with nonradiated mice (n = 10/group). *P < 0.05, compared with 8-week-old WT uninjured control mice. #P < 0.05, compared with respective 8-week-old mif−/− control mice. **P < 0.05, compared with irradiated 8-week-old WT mice.