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Ataluren corrects miR processing in endothelial cells and pulmonary artery smooth muscle cells (PASMCs). Cells were treated with 15 μM ataluren for 24 hours, then BMP9 (PAEC, L-EPC) or BMP4 (PASMC) for 4 hours. RNA was analyzed for miR-27a, normalized to RNU48. Results are shown as fold change of miR-27a with BMP treatment compared with vehicle. Means (±SEM) of nine replicates are shown.
