Table 3.

Effect of IFZN on hot plate reaction time and tail flick latency of mice.

Treatment	Dose mg/kg (p.o.)/(s.c.)	Tail flick latency (Second)	Hot plate reaction time (Second)
Control	5 (ml/kg)	4.28 ± 0.27	4.28 ± 0.27
Morphine	5	12.57 ± 0.41⁎	12.57 ± 0.41⁎
IFZN I	10	09.48 ± 0.34⁎	09.48 ± 0.34⁎
IFZN II	20	11.07 ± 0.39⁎	11.07 ± 0.39⁎⁎
IFZN III	30	11.33 ± 0.45⁎⁎	11.33 ± 0.45⁎⁎
IFZN III + Naloxone	30 + 1	09.35 ± 0.42⁎	–

Values reported as mean ± SEM (n = 6). The data were analyzed by one way ANOVA followed by the Dunnett’s test.

^⁎P < 0.05.

^⁎⁎P < 0.01 as compared with the control group. IFZN (cyclopeptide alkaloid fraction of leaves of Ziziphus nummularia).