Table 2. Main cerebral and systemic physiologic variables around perfusion CT time, according to brain perfusion pattern.
|
Oligemia |
Normal |
Hyperemia |
||
|---|---|---|---|---|
| Variable | n=6 | n=5 | n=5 | P value |
| Intracranial pressure (mm Hg) | 10±7 | 11±4 | 10±9 | NS |
| Cerebral perfusion pressure (mm Hg) | 70±6 | 72±9 | 70±9 | NS |
| PaO2 (mm Hg) | 158±73 | 117±24 | 111±20 | NS |
| PaO2/FiO2 | 298±124 | 338±61 | 316±140 | NS |
| PaCO2 (mm Hg) | 36±3 | 36±3 | 39±3a | 0.03 |
| SaO2 (%) | 99±1 | 99±1 | 98±1 | NS |
| Hemoglobin (g/L) | 106±18 | 117±19 | 110±19 | NS |
CT, computed tomography; FiO2, fraction of inspired oxygen; NS, not significant; PaCO2, partial pressure of carbon dioxide in arterial blood; PaO2, partial pressure of oxygen in arterial blood; SaO2, saturation level of oxygen in hemoglobin; TBI, traumatic brain injury.
Results are expressed as mean±s.d. Time from TBI to perfusion CT was 53±30 hours. Associations between brain/systemic physiologic variables and cerebral perfusion were performed using Wilcoxon's test with Bonferroni corrections for continuous variables.
a
P<0.05 for comparison between hyperemia and normal brain perfusion.