Fig. 2.

rAAV induced potent antitumor effect in vivo. a In C57BL/6J mice and b nude mice, the local expression of SLC in tumor sites was analyzed by Western-blot assay; c, d SLC-producing tumors showed a delayed progression and restrained in tumor weight when compared to rAAV-GFP tumors. No difference was observed between GFP-expressing and mock background tumors; e, f SLC-production was also associated with significantly improved survival. There was a worse survival in nude mice models, compared with C57BL/6J mice models. Bars SD, **p < 0.01 compared with rAAV-GFP group, *p < 0.05 compared with rAAV-SLC group; i.t., intra-tumor injection