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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Nat Immunol. 2013 Oct 6;14(11):10.1038/ni.2731. doi: 10.1038/ni.2731

Figure 1. BALB/c iNKT cells produce IL-4 in the steady state.

Figure 1

(a) Flow cytometric analysis shows hCD2 expression in conventional CD4 SP thymocytes (top row) and CD1d tetramer binding iNKT cells from thymus, spleen and liver (bottom three rows) of 7 week-old B6 and BALB/c KN2+/− mice. (b) Percentages and numbers of hCD2+ iNKT cells in thymus, spleen and liver of 7–8 week old B6-KN2 (N=4~10) and BALB/c-KN2 (N=4~13) mice. Horizontal bars indicate mean values. Unpaired two tailed t-tests were used to compare B6 and BALB/c mice. ***p<0.0001, **p=0.0095 (c) Representative FACS data of T-bet and Eomes expression in CD8 SP thymocytes of indicated mouse strains.