(a) Serum IgE concentrations measured by ELISA in indicated mice are shown. Unpaired two tailed t-tests were used to compare indicated two groups. N=5~16, ***
p<0.001, **p<0.01, *p<0.05 (b) Thymic CD8α+ or SIRPα+− DCs were sorted as described in experimental procedures and analyzed for the expression of CCL17 and CCL22 by real time RT-PCR. One-way ANOVA was used to compare CCL17 and CCL22 levels in SIRPα+ DCs. Pooled data from four independent experiments using 6 to 12 mice total in each group. ***
p<0.001, **
p<0.01, *p<0.05. Horizontal bars indicate mean values. Thy, thymocytes.