Table 2.
Baseline characteristics of study population by sex
| Variable | All patients | Sex | P value | |
|---|---|---|---|---|
| Female | Male | |||
| N | 1185 | 430 | 755 | <0.001 |
| Age (years) | 61.8 ± 11.1 | 60.8 ± 11.7 | 62.4 ± 10.7 | 0.016 |
| Medical history [n (%)] | ||||
| Hypertension | 1051 (88.7) | 365 (84.9) | 686 (90.9) | 0.002 |
| Diabetes | 489 (41.3) | 158 (36.7) | 331 (43.8) | 0.017 |
| Dyslipidemia | 918 (77.5) | 323 (75.1) | 595 (78.8) | 0.144 |
| Cardiovascular disease | ||||
| MI | 80 (6.8) | 8 (1.9) | 72 (9.5) | <0.001 |
| Angina | 129 (10.9) | 30 (7.0) | 99 (13.1) | 0.001 |
| Congestive heart failure | 67 (5.7) | 19 (4.4) | 48 (6.4) | 0.165 |
| ASO | 43 (3.6) | 9 (2.1) | 34 (4.5) | 0.033 |
| Stroke | 147 (12.4) | 36 (8.4) | 111 (14.7) | 0.002 |
| BMI (kg/m2) | 23.6 ± 3.8 | 23.2 ± 4.1 | 23.9 ± 3.5 | 0.002 |
| Blood pressure (mmHg) | ||||
| Systolic | 132.4 ± 18.1 | 131.2 ± 18.7 | 133.1 ± 17.6 | 0.081 |
| Diastolic | 75.9 ± 11.8 | 74.8 ± 12.0 | 76.5 ± 11.7 | 0.017 |
| Pulse pressure (mmHg) | 56.5 ± 13.9 | 56.4 ± 14.4 | 56.6 ± 13.7 | 0.776 |
| Creatinine (mg/dl) | 2.18 ± 1.09 | 1.84 ± 0.90 | 2.38 ± 1.13 | <0.001 |
| eGFR (ml/min/1.73 m2) | 28.61 ± 12.63 | 28.61 ± 13.00 | 28.61 ± 12.43 | 0.999 |
| Uric acid (mg/dl) | 7.21 ± 1.51 | 6.90 ± 1.51 | 7.38 ± 1.49 | <0.001 |
| Urinary protein (g/day) | 1.55 ± 2.13 | 1.30 ± 1.91 | 1.665 ± 2.22 | 0.081 |
| Urinary albumin (mg/gCr) | 1064.4 ± 1512.3 | 1013.0 ± 1593.8 | 1093.8 ± 1464.0 | 0.386 |
| Total chol (mg/dl) | 194.3 ± 43.6 | 207.6 ± 45.3 | 186.6 ± 40.7 | <0.001 |
| Non-HDL chol (mg/dl) | 140.7 ± 42.1 | 147.9 ± 44.3 | 136.55 ± 40.3 | <0.001 |
| LDL chol (mg/dl) | 110.6 ± 34.2 | 118.1 ± 35.2 | 106.3 ± 32.9 | <0.001 |
| HDL chol (mg/dl) | 53.9 ± 18.3 | 60.8 ± 19.3 | 50.0 ± 16.4 | <0.001 |
| Triglyceride (mg/dl) | 170.3 ± 115.2 | 160.5 ± 106.0 | 175.8 ± 119.8 | 0.036 |
| Calcium (mg/dl) | 9.01 ± 0.55 | 9.13 ± 0.54 | 8.95 ± 0.55 | <0.001 |
| Phosphorus (mg/dl) | 3.53 ± 0.69 | 3.77 ± 0.62 | 3.38 ± 0.68 | <0.001 |
| iPTH (pg/ml) | 105.6 ± 83.7 | 109.3 ± 88.0 | 103.4 ± 81.1 | 0.253 |
| CRP (mg/dl) | 0.27 ± 0.96 | 0.21 ± 0.44 | 0.30 ± 1.16 | 0.145 |
| A1C (%) | 5.98 ± 0.93 | 5.98 ± 0.99 | 5.98 ± 0.89 | 0.966 |
| Hemoglobin (g/dl) | 12.14 ± 1.84 | 11.53 ± 1.54 | 12.49 ± 1.91 | <0.001 |
| Medication [n (%)] | ||||
| Antihypertensive agent | 1095 (92.4) | 383 (89.1) | 712 (94.3) | 0.001 |
| ARB | 901 (76.0) | 313 (72.8) | 588 (77.9) | 0.070 |
| ACEI | 302 (25.5) | 103 (24.0) | 199 (26.4) | 0.394 |
| CCB | 685 (57.8) | 223 (51.9) | 462 (61.2) | 0.003 |
| β-Blocker | 315 (26.6) | 97 (22.6) | 218 (28.9) | 0.002 |
| Statin | 510 (43.0) | 214 (49.8) | 296 (39.2) | <0.001 |
| Diuretic | 403 (34.0) | 141 (32.8) | 262 (34.7) | 0.553 |
| Antiplatelet | 424 (35.8) | 124 (28.8) | 300 (39.7) | <0.001 |