Table 4.
Multivariate regression analyses of determinants of health related quality of life
| Coefficient | SE | 95% CI | p value | R squared | ||
| TOTAL SGRQ | ||||||
| Weight loss | 11.14 | 5.59 | −0.14 | 22.43 | 0.053 | |
| FEV1_post | 0.00 | 0.01 | −0.01 | 002 | 0.782 | Adjusted |
| Breathlessness | 22.91 | 6.20 | 10.41 | 35.41 | 0.001 | R2=0.35 |
| VAS past exercise | 0 24 | 0.12 | −0.01 | 0.49 | 0.060 | |
| SYMPTOM SGRQ | ||||||
| Weight loss | 5.17 | 7.65 | −10.26 | 20.61 | 0.502 | |
| FEV1_post | 0.00 | 0.01 | −0.02 | 0.02 | 0.845 | Adjusted |
| Breathlessness | 25.20 | 8.02 | 9.01 | 41.39 | 0.003 | R2=0.27 |
| Sputum | 18.30 | 11.94 | −5.79 | 4240 | 0.133 | |
| ACTIVITY SGRQ | ||||||
| Weight loss | 1037 | 6.98 | −3.72 | 2446 | 0.145 | |
| Breathlessness | 36.81 | 7.74 | 21.20 | 52.42 | 0.000 | Adjusted- |
| VAS past exercise | 026 | 0.15 | −0.05 | 057 | 0.099 | R2=0.42 |
| FEV1_post | 0.00 | 0.01 | −0.02 | 002 | 0.689 | |
| IMPACT SGRQ | ||||||
| Weight loss | 12.20 | 5.35 | 1.40 | 22.99 | 0.028 | |
| FEV1_post | 0.00 | 0.01 | −0.01 | 002 | 0.532 | Adjusted- |
| Breathlessness | 13.65 | 5.93 | 1.69 | 25.61 | 0.026 | R2=0.24 |
| VAS past exercise | 0.28 | 0.12 | 0.04 | 051 | 0.023 | |
CI-Confidence Interval; FEV1-Forced Expiratory Volume in one second; VAS-Visual Analogue Scale; SGRQ - St George's Respiratory Questionnaire; SE-Standard Error; Post - postbronchodilator
The model adjusted for age, sex and smoking with SGRQ ‘total’ ‘symptom’ activity and ‘Impact’ scores as dependent variables Significant variables at p<0.05, are in bold