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Microvascular alterations after ErbB2 inhibition alone or in combination with irradiation. a MVD per unit area expressed as number of microvessels per mm2. b ALP positive tissue areas as % of total tissue. c vWF positive tissue areas as % of total tissue *p < 0.05 compared to age-matched untreated controls. Each value represents the mean (±SEM) for minimal five mice per group. Ctrl control; Lap lapatinib; IR irradiation; IR+lap irradiation combined with lapatinib
