Figure 6.

Changes in Cx36 expression modulate ER stress-induced phosphorylation of AMPK in INS-1E cells. (a) Representative western blot and quantification of P-AMPK over AMPK levels in INS-1E cells transfected with a control siRNA (siCtrl) or two different Cx36 siRNAs (siCx36#1 and #2) and treated for 24 h with IL-1β+IFN-γ. (b) Representative western blot and quantification of P-AMPK over AMPK levels in INS-1E cells infected or not (NI) with the Ad-GFP or the Ad-Cx36 at various multiplicity of infection (MOI), as indicated, and treated for 24 h with IL-1β+IFN-γ. *P<0.05, **P<0.01 versus ctrl. ^#P<0.05 versus respective siCtrl condition or NI condition