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Limonene levels in mouse mammary tissue and plasma after four weeks of daily oral or topical limonene administration.
| Mammary tissue (µ M) |
Plasma (µ M) | Mammary tisue/Plasma ratio |
|
|---|---|---|---|
| 10% Topical (N = 4) |
47.95 ± 33.96a,b | 0.02 ± 0.01 | 4105 ± 4183 |
| 20% Topical (N = 4) |
46.00 ± 14.37b | 0.02 ± 0.01 | 3063 ± 2286 |
| 10% Oral (N = 4) |
44.55 ± 13.21b | 0.08 ± 0.11 | 1434 ± 1195 |
| 20% Oral (N = 4) |
115.39 ± 85.43b | 0.02 ± 0.01 | 4828 ± 2516 |
Mean ± SD;
Significantly higher than plasma (P < 0.05).
