Figure 5.

A438079 inhibits BzATP-induced [Ca²⁺]_i increase in SCs. (a) Representative time course of [Ca²⁺]_i levels indicated by Fluo-4 fluorescence intensities in SCs after exposure to different concentrations of BzATP. (b) Representative time course of [Ca²⁺]_i levels in SCs exposed to different concentrations of BzATP with A438079 (100 μM). (c) Quantification of Fluo-4 fluorescence intensities in SCs in the first 180 s (peak phase) after exposure to different concentrations of BzATP with or without A438079. ***P<0.001 (compared between groups exposed to the same concentration of BzATP with and without A438079), single factor ANOVA, n=3