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Myeloperoxidase (MPO)+ cells (dark red color), detected by Immunostaining, were mainly located in tubular lumens (e, f) and interstitial areas (b–e); and a few were also seen in tubular areas (a, c) and glomerular areas. MPO+ cells were significantly increased by IR and CsA but decreased by HBSP (g). The yellow arrow indicated a MPO+ cell with apoptotic feature (f). Data are expressed as mean number in the high power field of each group (mean ± SEM; n = 6). *P < 0.05; **P < 0.01.
