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. 2013 Aug 11;30(10):1327–1332. doi: 10.1007/s10815-013-0073-3

Table 1.

Binary regression analysis of the pronuclear morphological characteristics that may affect the blastocyst morphological factors

Response variable Predictor variable P OR CI: Lower CI: Upper
ICM alteration Halo normality 0.513 2.33 0.19 9.25
PN size 0.562 0.46 0.03 6.3
PN position 0.649 1.63 0.2 3.28
Number of NPB 0.035 2.51 1.2 3.34
Size of NPB 0.997 1.76 0.65 3.43
Distribution of NPB 0.185 0.18 0.01 2.27
TE alterations Halo normality 0.434 1.43 0.58 3.51
PN size 0.127 2.27 0.79 6.51
PN position 0.049 2.38 1.31 4.05
Number of NPB 0.196 0.86 0.21 1.55
Size of NPB 0.236 0.754 0.34 1.14
Distribution of NPB >0.001 6.03 2.31 15.77

Bold numbers are statistically significant

PN pronuclear, NPB nucleolar precursor bodies, ICM Inner cell mass, TE trophectoderm cells, OR odds ratio, and CI confidence interval

ICM and TE graded according to the Istanbul consensus workshop on embryo assessment [25]