Table 2.

Associations with continuous remission after 1 year

	Number	Univariate analysis	Multivariate analysis
Female gender	n = 51	0.7 (0.2–2.3)	0.6 (0.1–2.9)
Age (continuous variable)		1.0 (0.98–1.04)	1.0 (0.96–1.06)
Age ≤ 40 years	n = 50	1	n.a.
Age 40–63 years	n = 42	2.2 (0.4–12.1)	n.a.
Age >63 years	n = 47	1.2 (0.3–4.7)	n.a.
Immunosuppressiona	n = 28	1.1 (0.2–5.6)	0.9 (0.1–6.9)
ASA scoreb		1.2 (0.5–2.7)	0.9 (0.2–2.8)
Delay implantation-infection		1.0 (0.98–1.06)	1.0 (0.97–1.09)
≤ 5 months	n = 71	1	1
> 5 months	n = 68	0.5 (0.1–1.9)	0.5 (0.1–2.5)
Infection due to S. aureus	n = 73	2.0 (0.6–7.3)	n.a.
Coagulase-negative staphylococci	n = 20	1.7 (0.2–14.4)	n.a.
Pseudomonas spp.	n = 7	0.2 (0.03–1.07)	0.1 (0.01–0.81)
Tibial implants	n = 69	1.2 (0.3–4.1)	n.a
Upper extremity implants	n = 15	1.1 (0.1–9.6)	n.a
Plates	n = 75	0.1 (0.01–0.82)	0.1 (0.01–0.90)
Nails	n = 24	2.2 (0.3–18.0)	n.a.
Total antibiotic therapy (continuous variable)		1.0 (0.98–1.01)	1.0 (0.98–1.01)
≤ 42 days	n = 78	1	1
43–63 days	n = 10	0.2 (0.1–1.1)	0.1 (0.1–2.5)
> 63 days	n = 51	0.3 (0.1–1.3)	0.2 (0.1–1.1)
Parenteral therapy (continuous variable)		1.0 (0.97–1.04)	1.0 (0.96–1.06)
≤ 4 days	n = 62	1	1
> 4 days	n = 77	1.0 (0.3–3.6)	0.9 (0.2–4.1)
Implant retainedc	n = 20	2.4 (0.6–10.1)	4.6 (0.5–45.0)
Second lookd	n = 114	1.0 (0.2–5.0)	0.8 (0.1–4.1)

Results are displayed as OR (95 % CI). Variables in boldface are statistically significant (two-tailed p value <0.05)

^aDiabetes mellitus, immunosuppressive therapy, dialysis, Child’s class C cirrhosis, active cancer

^bASA score, continuous variable

^cImplant not removed, only debridement

^dSecond look or debridement