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. 2012 Nov 20;35(6):2027–2044. doi: 10.1007/s11357-012-9492-9

Fig. 5.

Fig. 5

Bax and Bcl-2 polypeptides. a No changes of Bcl-2 protein levels were observed by CR (AL-Soy vs. CR-Soy). b Levels of Bcl-2 polypeptide were also unaltered as a function of dietary fat source in animals fed under CR. c Despite a lack of changes in Bcl2 levels, CR produced a dramatic decrease of Bax polypeptide (AL-Soy vs. CR-Soy, *p < 0.05). d Bax levels were also strongly modulated by lipid source in animals fed under CR (bCR-Lard vs. CR-Soy, p < 0.05; cCR-Lard vs. CR-Fish, p < 0.01). Linear trend as a function of dietary fat source was statistically significant with p < 0.01 (#). e A trend towards higher Bcl-2/Bax ratio was observed in CR-Soy compared to AL-Soy, although no significant differences were observed in this case. f Bcl-2/Bax ratio was significantly higher in the CR-Fish group compared with CR-Lard (a p < 0.05). Additionally, linear trend as a function of dietary fat source was statistically significant with p < 0.01 (#). Data are mean ± SEM (n = 4)