Table 2.

Univariate Cox regression analyses of all-cause and cardiovascular mortalities

	Units of increase	Hazard ratio, 95 CI, and P value
		All-cause mortality	CV mortality
Age	1 year	1.14 (1.12–1.15), P < 0.001	1.17 (1.14–1.19), P < 0.001
BMI	1 kg/m2	0.97 (0.95–1.00), P = 0.05	0.98 (0.93–1.02), P = 0.36
Male sex		0.78 (0.64–0.95), P = 0.02	0.84 (0.60–1.17), P = 0.30
Smoking	0 = no; 1 = yes	1.13 (0.92–1.38), P = 0.24	0.79 (0.56–1.13), P = 0.18
Diabetes	0 = no; 1 = yes	1.26 (0.95–1.67), P = 0.11	1.22 (0.76–1.96), P = 0.41
Systolic pressure	5 mmHg	1.06 (1.04–1.09), P < 0.001	1.09 (1.05–1.14), P < 0.001
Diastolic pressure	5 mmHg	1.07 (1.01–1.13), P = 0.04	1.10 (0.99–1.21), P = 0.06
Heart rate	5 beats/min	1.07 (1.02–1.12), P = 0.002	1.06 (0.99–1.14), P = 0.12
Calcium	1 mg/dL	0.60 (0.47–0.77), P < 0.001	0.63 (0.42–0.95), P = 0.03
Glucose	5 mg/dL	1.02 (1.01–1.04), P = 0.02	1.02 (0.99–1.06), P = 0.11
HOMA index	1 UI/L/mmol/L	1.01 (0.95–1.07), P = 0.80	1.05 (0.97–1.14), P = 0.24
Hemoglobin	1 g/dL	0.79 (0.73–0.85), P < 0.001	0.77 (0.69–0.87), P < 0.001
Total cholesterol	20 mg/dL	0.85 (0.81–0.90), P < 0.001	0.91 (0.84–0.99), P = 0.04
Triglycerides	20 mg/dL	1.02 (0.99–1.04), P = 0.27	1.03 (0.99–1.07), P = 0.17
Homocysteine	1 μMol/L	1.05 (1.04–1.06), P < 0.001	1.06 (1.04–1.08), P < 0.001
ADMA	0.1 μMol/L	1.73 (1.52–1.97), P < 0.001	1.81 (1.47–2.23), P < 0.001
Creatinine clearance	1 mL/min/1.73 m2	0.98 (0.97–0.98), P < 0.001	0.97 (0.96–0.98), P < 0.001
l-arginine	1 μMol/L	1.01 (1.001–1.01), P = 0.01	1.01 (0.99–1.02), P = 0.06
CRP	1 mg/L	1.02 (1.02–1.03), P < 0.001	1.03 (1.02–1.04), P < 0.001
Albuminuria (>5 mg/dL)	0 = no; 1 = yes	2.65 (1.95–3.61), P < 0.001	2.88 (1.76–4.70), P < 0.001
Cardiovascular comorbidities	0 = no; 1 = yes	2.76 (2.24–3.39), P < 0.001	4.99 (3.40–7.32), P < 0.001
On anti-hypertensive therapy	0 = no; 1 = yes	1.53 (1.25–1.87), P < 0.001	2.49 (1.77–3.50), P < 0.001

Data are expressed as hazard ratio, 95 % confidence, and P values