Fig. 6.

The ability of cell proliferation determined by BrdU and MTT assays. a Percentage of BrdU-positive glomerular mesangial cells. b GMCs growth data determined by absorbance units at 450 nm in the MTT assay of young and aged rats. Mean ± SE. *P < 0.05, compared to young GMCs, n = 3–7. b, d Summary of data showing percentage of BrdU-positive young GMCs (b) and cell growth of young GMCs (d) treated by scrambled siRNA control (Con-siRNA), STIM 1, or Orai 1 siRNA transfection. Mean ± SE. *P < 0.05, compared to GMCs transfected with scrambled siRNA control, n = 3–7