Table 1.
LV function
| A: Short-term calorie restriction | Prior to ST CR and ND | Old ST ND | Old ST CR |
| Number | 8 | 8 | 6 |
| Age (months) | 20 | 22 | 22 |
| BW (g) | 27 ± 1 | 27 ± 1 | 23 ± 1*† |
| LVEF (%) | 63 ± 1 | 65 ± 1 | 74 ± 1*† |
| Fractional shortening (%) | 28 ± 2 | 29 ± 1 | 36 ± 1*† |
| Heart rate (bpm) | 438 ± 20 | 492 ± 12* | 505 ± 28* |
| LVEDD (mm) | 3.6 ± 0.1 | 3.6 ± 0.1 | 3.0 ± 0.2*† |
| LVESD (mm) | 2.6 ± 0.1 | 2.6 ± 0.1 | 1.9 ± 0.1*† |
| EDWT (mm) | 0.74 ± 0.04 | 0.89 ± 0.04 | 0.85 ± 0.06 |
| B: Long-term calorie restriction | Young ND | Old LT ND | Old LT CR |
| Number | 8 | 6 | 6 |
| Age (months) | 4 | 26 | 26 |
| BW (g) | 25 ± 1 | 26 ± 1 | 18 ±0.4**†† |
| LVEF (%) | 71 ± 1 | 53 ± 6** | 71 ± 2†† |
| Fractional shortening (%) | 34 ± 1 | 23 ± 3** | 34 ± 1†† |
| Heart rate (bpm) | 422 ± 19 | 453 ± 10 | 482 ± 26** |
| LVEDD (mm) | 3.7 ± 0.1 | 3.1 ± 0.1** | 3.0 ± 0.2** |
| LVESD (mm) | 2.4 ± 0.1 | 2.3 ± 0.2 | 2.1 ± 0.1** |
| EDWT (mm) | 0.82 ± 0.03 | 0.97 ± 0.02** | 0.77 ± 0.04†† |
ST short term, ND normal diet, CR calorie restriction, LT long term, LVEF left ventricular ejection fraction, LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, EDWT end-diastolic wall thickness
*p < 0.05 vs. prior to ST CR; †p < 0.05 vs. old ST ND; **p < 0.05 vs. young ND; ††p < 0.05 vs. old LT ND