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. Author manuscript; available in PMC: 2013 Nov 12.
Published in final edited form as: J Thromb Haemost. 2009 Aug 19;7(11):10.1111/j.1538-7836.2009.03594.x. doi: 10.1111/j.1538-7836.2009.03594.x

Figure 2.

Figure 2

Two different tests of VWF function are shown. The VWF-platelet binding assay uses a gain-of-function GPIb to induce binding to plasma VWF. The black bars represent the mean ratio of VWF-platelet binding/VWF:Ag for the P1467S index case, Caucasian, and African American (AA) controls from the ZPMCB-VWD. The grey bars represent the mean VWF:RCo/VWF:Ag ratio, as measured in the clinical laboratory, for each group. Error bars denote 1 SD. While the VWF-platelet binding/VWF:Ag ratios were similar for the P1467S index case and controls, the P1467S index case had a markedly reduced VWF:RCo/VWF:Ag ratio.