Table 1. OxLDL and Thrombin induce phosphorylation of p38, c-JNK and ERK1/2 in platelets.
OP | P-value | RP | P-value | TP | |
Pselectin µg/ml | 34.40± 6.50 | 0.001 | 11.29±2.58 | 0.001 | 46.86±6.44 |
Phospho/total ERK(%) | 29.35±4.57 | 0.001 | 13.29±4.60 | 0.001 | 64.45±4.92 |
Phospho/total JNK (%) | 87.70±6.15 | 0.001 | 20.07±4.80 | 0.001 | 89.27±8.03 |
Phospho/total P38 (%) | 74.44±8.73 | 0.001 | 12.33±5.04 | 0.001 | 81.52±8.46 |
Data are shown as the means (SD), Significant P- Value < 0.05. RP=Resting Platelets, OP=Oxidized-LDL treated Platelets , TP=Thrombin treated Platelets |