Table 4.

Comparison of prognostic values of subjective assessment, HE4 serum level, CA125 serum level in group of 145 “suspicious” ovarian tumors analyzed

Test	Sens	Spec	PPV	NPV	ACC	AU ROC
Subjective ultrasound assessment	93.3	90.6	87.5	95.1	91.7	0.923
HE4	80.0	91.7	87.3	86.7	86.9	0.891
CA125 (cut-off 35 IU/ml)	85.7	74.7	69.6	88.7	79.1	0.902
CA125 (cut-off 95 IU/ml)	78.6	91.7	86.3	86.5	86.4	0.902

Sens sensitivity, Spec specificity, PPV positive predictive value, NPV negative predictive value, ACC accuracy, AU ROC area under ROC