Table 2.

Age, clinical symptoms, blood, and fecal biomarkers for patients with toxigenic Clostridium difficile infection (CDI). The ranges for each biomarker are included in parentheses (min, max) and a significant difference (p < 0.05) between the mean ± standard error (SE) and percentages is noted with an asterisk (*) when compared to the moderate and mild groups and with a double asterisk (**) when compared to the mild group. Comparisons of severe CDI versus moderate/mild cases based on a one-way analysis of variance (ANOVA) are noted with bold p-values

Disease severity	Mean age (years)	Mean ± SE (μg/g) fecal lactoferrin (min, max)	Mean ± SE (109/L) WBC (min, max)	Mean ± SE (mg/dL) serum albumin (min, max)	Reported pain (%)	Mean stools (per day)	Tissue culture positive (%)	027 infection (%)
Severe	66	961 ± 303* (2, 4,672)	19 ± 3.2* (7.5, 66.1)	2.2 ± 0.2* (0, 3.2)	62 %	9	91 %**	71 %*
Moderate	67	292 ± 42 (1, 1,391)	13 ± 0.9 (1.6, 28.6)	2.7 ± 0.1 (1.8, 3.6)	65 %	8	83 %**	37 %
Mild	69	73 ± 52 (3, 376)	9 ± 1.3 (4.3, 14.2)	2.5 ± 0.2 (1.8, 3.1)	29 %	5	29 %	29 %
Severe versus moderate/mild CDI	p = 0.8443	p = 0.0003	p = 0.0048	p = 0.0083	p = 0.9370	p = 0.4298	p = 0.1414	p = 0.0043