Table 1.
TE products currently available on the medical market
| Intended use | Product name (Company) | Cell type used | Scaffold/material used |
|---|---|---|---|
| Wound healing, burns, diabetic and venous leg ulcers | Dermagraft® (Shire regenerative medicine, st Helier, Jersey) | Allogenic fibroblasts | Bioabsorbable polyglactin mesh |
| Apligraf (Organogenesis Inc., Canton, MA, USA) | Allogenic fibroblasts and keratinocytes | Type I bovine collagen matrix | |
| MySkin (Altrika Ltd, Sheffield, UK) | Autologous keratinocytes | Silicone coated with a chemically controlled plasma polymer film | |
| OrCell (Forticell Bioscience, Englewood Cliffs, NJ, USA) | Allogenic fibroblasts and layer of keratinocytes | Type I bovine collagen sponge | |
| PolyActive (HC Implants BV, leiden, Netherlands) | Autologous cultured fibroblasts and keratinocytes | A compound of polyethyleneoxide terephthalate and polybutylene terephthalate | |
| Cartilage defects | Hyalograft 3D (Fidia Farmaceutici s.p.a.) | Autologous chondrocytes | Hyaluronic acid |
| Bioseed-C (BioTissue Technologies, GmbH, Freiburg, Germany) | Autologous chondrocytes | A polyglycolic/polylactic acid and polydioxane based material | |
| CaReS® (Arthro-Kinetics, Germany) | Autologous chondrocytes | Rat collagen type I | |
| J-tec, Japan Tissue Engineering Co | Autologous chondrocytes | Atelocollagen gel | |
| Novocart Inject Novocart 3D (Melsungen, Germany) | Autologous chondrocytes | Polymerizable hydrogel Collagen type I | |
| Bony voids, gaps | FormaGraft (NuVasive, San Diego, CA, USA) | Autologous bone marrow aspiratea | Hydroxyapatite, beta-tricalcium phosphate and bovine collagen granules |
| Healos® (DePuy Synthes, Warsaw, IN, USA) | Autologous bone marrow aspirate | Type I bovine collagen fibers coated with hydroxyapatite | |
| Vitoss® Foam (Orthovita/Stryker, Malvern, PA, USA) | Autologous bone marrow aspiratea | Β-TCP, Collagen, bioactive glass | |
| Grafton (Biohorizons, Birmingham, AL, USA | Autologous bone marrow aspiratea | DBM | |
| CopiOs (Zimmer, Warsaw, IN, USA) | Autologous bone marrow aspirate | Autologous bone marrow aspirate |
aAs an option