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. 2013 Oct 17;60(11):1089–1118. doi: 10.1007/s12630-013-0019-3

Table 2.

Effectiveness of a selection of alternatives to direct laryngoscopy in the difficult airway

Population Published benefit Level(s) of evidence & references
LMA Fastrach™ (LMA North America Inc., San Diego, CA)
 Patients with failed Macintosh direct laryngoscopy (DL) Successful ventilation/intubation C: (43,70,80-85)
 Patients with predicted difficult intubation by DL Successful ventilation/intubation

B: (86-88)

C: (42,85,89-94)

 Obese patients Successful ventilation/intubation

B: (95)

C: (96)

 Patients with manual in-line stabilization Successful ventilation/intubation

B: (97)

C: (43,89,98)

air-Q™ (Cookgas LLC, St. Louis, MO)
 Patients with difficult laryngoscopy Successful intubation (endoscopic-aided) C: (92,99,100)
Bronchoscopic-aided intubation through a supraglottic device
 Patients with failed Macintosh DL Successful ventilation/intubation C: (43)
 Patients with predicted difficult intubation by DL Successful ventilation/intubation B: (86) C: (101)
Bronchoscopic- and Aintree catheter-aided intubation through a supraglottic device
 Patients with predicted difficult intubation by DL Successful intubation B: (102) C: (103-105)
Intubating lighted stylets
 Patients with failed Macintosh DL Successful intubation C: (106)
 Patients with predicted difficult intubation by DL Successful intubation A: (107) B: (108)
 Patients with MILS Successful intubation B: (109)
GlideScope® videolaryngoscope (Verathon Medical Canada ULC, Burnaby, BC)
 Patients with failed Macintosh DL Successful intubation B: (78,110) C: (111-113)
 Patients with predicted difficult intubation by DL Improved view A: (114,115) C: (116)
Successful intubation A: (117) B: (78,118,119) C: (115)
 Patients with MILS Improved view A: (120) B: (121) C: (122-124)
Successful intubation B: (125) C: (121)
 Patients with ankylosing spondylitis Successful intubation C: (126,127)
 Obese patients Improved view A: (128-130) B: (131)
Successful intubation A: (129) B: (95,130) C: (132)
Awake intubation C: (133)
 Patients with upper airway tumours Improved view A: (134)
McGrath® Series 5 video laryngoscope (LMA North America Inc., San Diego, CA)
 Patients with failed Macintosh DL Successful intubation C: (135,136)
 Patients with predicted difficult intubation by DL Improved view C: (137)
Successful intubation B: (138)
Awake intubation B: (139)
 Patients with MILS Successful intubation B: (140)
 Obese patients Improved view A: (128)
Storz C-MAC® (with Macintosh blade) (Karl Storz Endoscopy, El Segundo, CA)
 Patients with failed Macintosh DL Improved view B: (141)
Successful intubation B: (141)
 Patients with predicted difficult intubation by DL Successful intubation A: (142) B: (138)
 Obese patients Improved view A: (128)
Storz C-MAC® (with D-blade) (Karl Storz Endoscopy, El Segundo, CA)
 Patients with failed Macintosh DL Improved view B: (143)
Successful intubation B: (143)
 Patients with predicted difficult intubation by DL Improved view B: (144)
Successful intubation B: (144)
Ambu® Pentax Airway Scope (Ambu Inc., Glen Burnie, MD)
 Patients with failed Macintosh DL Successful intubation B: (145-147) C: (148)
 Patients with predicted difficult intubation by DL Successful intubation A: (117)
 Patients with MILS Improved view A: (120) B: (123) C: (149)
Successful intubation A: (120,150) B: (123) C: (149)
Airtraq (Southmedic Inc., Barrie, ON)
 Patients with failed Macintosh DL Successful intubation C: (151)
 Patients with predicted difficult intubation by DL Faster intubation; reduction in intubation difficulty score B: (152) C: (153)
Successful intubation C: (153)
 Patients with upper airway tumours Improved view A: (134)
Flexible bronchoscopic intubation
 Anesthetized patients with failed Macintosh DL Successful intubation B: (154,155) C: (83)
Successful intubation (with use of a laryngeal mask airway and Aintree catheter) B: (102)
 Patients with predicted difficult intubation by DL Successful intubation A: (86) B: (87) C: (139,156)
Successful awake intubation B: (139)
 Anesthetized patients with MILS Successful intubation B: (157)
Clarus Video System (Clarus Medical, St. Paul, MN)
 Patients with predicted difficult intubation by DL Successful intubation B: (158)
 Patients with C-spine immobilization or injury Successful intubation A: (159)
Storz Bonfils intubation endoscope (Karl Storz Endoscopy, El Segundo, CA)
 Patients with failed Macintosh DL Successful intubation C: (160-162)
 Patients with predicted difficult intubation by DL Successful intubation; awake intubation B: (88) C: (163-165)
Clarus Shikani optical stylet (Clarus Medical, St. Paul, MN)
 Patients with MILS Successful intubation B: (121) C: (166)
Clarus Levitan optical stylet (Clarus Medical, St. Paul, MN)
 Patients with simulated difficult DL Successful intubation B: (74)

DL = direct laryngoscopy; MILS = manual in-line stabilization