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Effect curves of (A) polymer concentration, (B) ultrasonic time, (C) polyvinyl alcohol (PVA) concentration, and (D) water and oil phase volume ratio (W/O) on the particle size of paclitaxel-loaded six-arm star-shaped poly(lactic-co-glycolic acid) nanoparticles.
Notes: A polymer concentration of 30 mg/mL, ultrasonic time of 8 minutes, PVA concentration of 1%, and W/O of 3/1 were chosen as the optimal conditions when the particle size was at a minimum.
