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. 2013 Nov 7;8:4315–4326. doi: 10.2147/IJN.S51629

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© 2013 Chen et al. This work is published by Dove Medical Press Ltd, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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(A) Particle size and (B) paclitaxel loading capacity of paclitaxel-loaded six-arm star-shaped poly(lactic-co-glycolic acid) nanoparticles (6-s-PLGA-PTX-NPs) at baseline and after 1 month. Paclitaxel-loaded linear poly(lactic-co-glycolic acid) nanoparticles (L-PLGA-PTX-NPs) were tested as the control.

Notes: Bars represent mean ± standard deviation (n=3). No obvious change was observed in mean particle size or drug-loading capacity of the 6-s-PLGA-PTX-NPs during storage. This indicates the prepared 6-s-PLGA-PTX-NPs had satisfactory stability in both aqueous solution and lyophilized powder form at 4°C.