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. 2013 Nov 7;8:4291–4302. doi: 10.2147/IJN.S51837

Table 2.

LNC characteristics: particle size, polydispersity, and zeta potential of blank and paclitaxel or DiI/DiD-loaded lipid nanocapsules, and drug payload of paclitaxel-loaded lipid nanocapsules

Batch name Mean particle size (nm) Polydispersity index Zeta potential (mV) Drug payload (mg/g)
Blank 55-LNC 55.9 ± 0.6 0.042 ± 0.007 −9.4 ± 0.8
25-LNC of Paclitaxel 27.0 ± 0.0 0.062 ± 0.007 −4.8 ± 0.5 1.79 ± 0.03
55-LNC of paclitaxel 54.7 ± 0.4 0.038 ± 0.008 −6.7 ± 1.1 1.86 ± 0.01
110-LNC of paclitaxel 118.3 ± 2.1 0.071 ± 0.016 −5.4 ± 0.4 1.27 ± 0.00
55-LNC of DiI/DiD 58.0 ± 2.1 0.166 ± 0.081 15.9 ± 1.8

Abbreviations: DiD, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine perchlorate; DiI, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; LNC, lipid nanocapsules.