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. 2013 Nov 12;8(11):e79963. doi: 10.1371/journal.pone.0079963

Figure 1. Renal expression of the endothelin system components in adriamycin nephropathy.

Figure 1

Mice were treated with saline or adriamycin (10 mg/kg) and sacrificed at the indicated time points. RNA was extracted from harvested kidneys and subjected to quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR) analysis. The mRNA expression of the ETA receptor (A), ETB receptor (B), and ET-1 (C) is presented. *P < 0.05 compared to 3 week and 5 week adriamycin groups. †P < 0.05 compared to saline controls.