Figure 1.

Therapeutic strategies in Alzheimer’s disease. Based on these cellular and pathological changes, multiple therapeutic strategies have been developed, including Aβ-immunotherapy, anti-phosphorylated tau therapy, anti-inflammatory therapy, antioxidant therapy, cholinergic therapy, cell cycle therapy, hormonal therapy, and inhibition of GSK3β activity. GSK3β is a multiple functional protein and inhibition of GSK3β activity may affect several pathways that are involved in Alzheimer’s disease pathogenesis.