Schematic of the genomic context of lncRNAs and a summary of their known functions.
LincRNA: epigenetic changes, maintenance of pluripotency and lineage commitment control.
NATs: alternative splicing, translation control, RNA interference, X-chromosome inactivation.
lintRNA: chromatin modification and organization, guidance of ribonucleoproteins and creation of scaffolds for their assembly. Overlapping: Chromatin modification.