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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Oral Dis. 2013 Jun 20;20(3):226–235. doi: 10.1111/odi.12142

Table 1.

Non-coding RNA types

Type Sub Type Symbol Size (nt) Localization Function References
Long non-coding RNA Natural Antisence NATS or aRNA ~110-130 Cytoplasm Regulates protein localization, mRNA translation and stability (Mercer & Mattck, 2013, Carrieri et al., 2012, Gong & Maquat, 2011, Willingham et al., 2005)

Long Intronic RNA lintRNA* 200 to ~100.000 Nucleus/Cytoplasm Epigenetic modulator, histone modification, DNA modification (Mercer & Mattick, 2013, Rinn et al., 2007)

Long intergenic non-coding RNAs lincRNA 200 to ~100.000 Nucleus Epigenetic modulator, histone modification, DNA modification (Khalil et al., 2009, Mercer & Mattick, 2013, Tsai et al., 2010)

Short non-coding RNA Small cytoplasmic scRNA ~60-120 Cytoplasm Structure Ribonucleoproteins (Verhagen & Pruijn, 2011, Selvakumar et al., 2012, Perreault et al., 2007)

Small nuclear RNA snRNA ~150 Nucleus RNA biogenesis and processing (West, 2012)

Small nucleolar RNA snoRNA ~130 Nucleous Chemically modify, mature, and stabilize rRNAs, Regulate alternative splicing (Terns & Terns, 2002, Cavaille & Bachellere, 1998, Kishore et al., 2010)

MicroRNA miRNA 17-25 Cytoplasm Post-transcriptional control protein expression (Kim et al., 2009)

PIWI-interacting RNAs piRNA 25–33 Cytoplasm Transposon silencing, heterochromatin modification in germinal cells (Siomi et al., 2011, Pillai & Chuma, 2012)

MicroRNA offset moRNA ~20 Cytoplasm Functonal regulators of protein expression (hypothetical) (Shi et al., 2009, Umbach et al., 2010)

5'-capped promoter-associated small RNAs PASRS 30-35 Nucleus Functional regulators of gene transcription (hypothetical) (Affymetrix ENCODE Transcriptome Project, 2009)

Small Interfering RNAs siRNA 21-23 Cytoplasm Regulate post-transcriptional expression (Xia et al., 2013, Lejeune & Allshire, 2011)
*

lintRNA is not the official acronym, use here to simplify text. Stand for Long intronic RNA