Table 1.
Type | Sub Type | Symbol | Size (nt) | Localization | Function | References |
---|---|---|---|---|---|---|
Long non-coding RNA | Natural Antisence | NATS or aRNA | ~110-130 | Cytoplasm | Regulates protein localization, mRNA translation and stability | (Mercer & Mattck, 2013, Carrieri et al., 2012, Gong & Maquat, 2011, Willingham et al., 2005) |
Long Intronic RNA | lintRNA* | 200 to ~100.000 | Nucleus/Cytoplasm | Epigenetic modulator, histone modification, DNA modification | (Mercer & Mattick, 2013, Rinn et al., 2007) | |
Long intergenic non-coding RNAs | lincRNA | 200 to ~100.000 | Nucleus | Epigenetic modulator, histone modification, DNA modification | (Khalil et al., 2009, Mercer & Mattick, 2013, Tsai et al., 2010) | |
Short non-coding RNA | Small cytoplasmic | scRNA | ~60-120 | Cytoplasm | Structure Ribonucleoproteins | (Verhagen & Pruijn, 2011, Selvakumar et al., 2012, Perreault et al., 2007) |
Small nuclear RNA | snRNA | ~150 | Nucleus | RNA biogenesis and processing | (West, 2012) | |
Small nucleolar RNA | snoRNA | ~130 | Nucleous | Chemically modify, mature, and stabilize rRNAs, Regulate alternative splicing | (Terns & Terns, 2002, Cavaille & Bachellere, 1998, Kishore et al., 2010) | |
MicroRNA | miRNA | 17-25 | Cytoplasm | Post-transcriptional control protein expression | (Kim et al., 2009) | |
PIWI-interacting RNAs | piRNA | 25–33 | Cytoplasm | Transposon silencing, heterochromatin modification in germinal cells | (Siomi et al., 2011, Pillai & Chuma, 2012) | |
MicroRNA offset | moRNA | ~20 | Cytoplasm | Functonal regulators of protein expression (hypothetical) | (Shi et al., 2009, Umbach et al., 2010) | |
5'-capped promoter-associated small RNAs | PASRS | 30-35 | Nucleus | Functional regulators of gene transcription (hypothetical) | (Affymetrix ENCODE Transcriptome Project, 2009) | |
Small Interfering RNAs | siRNA | 21-23 | Cytoplasm | Regulate post-transcriptional expression | (Xia et al., 2013, Lejeune & Allshire, 2011) |
lintRNA is not the official acronym, use here to simplify text. Stand for Long intronic RNA