. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: J Electrocardiol. 2013 Sep 6;46(6):10.1016/j.jelectrocard.2013.08.006. doi: 10.1016/j.jelectrocard.2013.08.006

Table 1. J-wave Syndromes: Similarities and Differences.

	J Wave Syndromes
	Inherited				Acquired
	ER in lateral leads ERS Type 1	ER in inferior or infero-lateral leads ERS Type 2	Global ER ERS Type 3	Brugada Syndrome	Ischemia- mediated VT/VF	Hypothermia- mediated VT/VF
Anatomic Location	Antero-lateral left ventricle	Inferior left ventricle	Left and right ventricles	Right ventricle	Left and right ventricles	Left and right ventricles
Leads Displaying J point/ J-wave	I, V4-V6	II, III, aVF	Global	V1-V3	Any of 12 leads	Any of 12 leads
Response of J wave /ST Elevation to: Bradycardia or pause Na+ channel blockers					N/A N/A	N/A N/A
Sex Dominance	Male	Male	Male	Male	Male⁷¹,⁷²	Either gender
VT/VF	Rare Common in healthy athletes^{12, 13, 34}	Yes^16,73	Yes, Electrical storms^{17, 74}	Yes	Yes	Yes
Response of to Quinidine: J wave /ST elevation VT/VF					Limited data	⁷⁵
Response of to Isoproterenol: J wave /ST elevation VT/VF			Limited data		N/A	N/A

ER= early repolarization; ERS=early repolarization syndrome; N/A=not available; VF=ventricular fibrillation; VT=ventricular tachycardia. Modified from ⁸, with permission.