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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Nanomedicine (Lond). 2013 Feb 28;8(12):10.2217/nnm.12.200. doi: 10.2217/nnm.12.200

Figure 3. The effects of tetraiodothyroacetic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles on FGF2-induced angiogenesis measured by the chick chorioallantoic membrane assay.

Figure 3

(A) Photomicrographs of representative chick chorioallantoic membranes treated with free tetrac or T-PLGA-NPs. Chick chorioallantoic membranes were also treated with FGF2 or PBS as a positive and a negative control, respectively. (B) Quantification of angiogenesis inhibition by tetrac versus T-PLGA-NPs. Data represent the number of branch points and were normalized to the negative control (PBS). Data are expressed as percentage inhibition of angiogenesis induced by FGF2 alone (mean ± standard error of the mean).

*p ≤ 0.01.

PBS: Phosphate-buffered saline; tetrac: Tetraiodothyroacetic acid; T-PLGA-NPs: Tetraiodothyroacetic acid conjugated to poly(lactic-co-glycolic acid) nanoparticles.