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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Eur J Oral Sci. 2013 Sep 25;121(6):10.1111/eos.12088. doi: 10.1111/eos.12088

Figure 3. Failure to process DSPP into fragments leads to loss of epithelium attachment in the interdental region.

Figure 3

At 3- and 6-months of age, H & E staining showed that the interdental epithelial attachment between the first and second mandibular molars of the WT (A and E) and Dspp-KO/normal-Tg mice (C and G) was at the cemento-enamel junction (CEJ) (indicated with a black arrow), whereas the Dspp-KO (D and H) and Dspp-KO/D452A-Tg mice (B and F) showed alveolar bone loss with an apically recessed epithelial attachment (black arrows denote the CEJ; red arrows indicate the actual epithelial attachment). Bar: 100 μm.