Figure 5.

(a) CFos levels were significantly elevated in the motor cortex of EW males compared to pair-fed controls at 1 day EW; there was no significant increase in cFos levels in EW intact females at both 1 and 3 days EW. OVX females showed a significant elevation of cFos compared to controls, only at 1 day EW. Data are presented as means ± SEM counts per 15mm²; *significantly different from controls, P < 0.05, N = 4-8 animals per treatment condition. (b) BDNF levels were significantly elevated in the motor cortex of EW males compared to pair-fed controls at 3 days EW only, and in EW intact females only, compared to pair-fed controls at 1 day EW. Data are presented as means ± SEM counts per 15mm²; *significantly different from controls, P < 0.001, N = 4-8 animals per treatment condition