Table 1.
IC50 of the bromophenols obtained and a positive control on glucose 6-phosphate dehydrogenase (G6PD) reaction.
| Compound | IC50a (μM) |
|---|---|
| 1 | 76.6 ± 1.1 |
| 2 | >370 (37.6 ± 1.6%) b |
| 3 | >340 (35.7 ± 4.4%) c |
| 4 | 4.01 ± 0.30 |
| 5 | 0.85 ± 0.10 |
| Epigallocatechin gallate | 7.70 ± 0.14 |
a Mean ± SD (n = 3). Inhibition assay was carried out at the substrate glucose 6-phosphate and NADP+ concentrations of 3.0 and 0.3 mM, respectively; b Inhibition (%) of compound 2 at the concentration of 370 μM; c Inhibition (%) of compound 3 at the concentration of 340 μM.