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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Bioorg Med Chem. 2013 Aug 28;21(21):10.1016/j.bmc.2013.08.034. doi: 10.1016/j.bmc.2013.08.034

Table 1.

Biodistribution 90 min post administration of 99mTc labeled study and control MORFs to mice receiving either live or heat killed K. pneumoniae 2 h earlier.

Live Heat killed

Tissue Study MORF Control MORF Study MORF Control MORF
Liver 0.19 (0.06) 0.18 (0.07) 0.17 (0.03) 0.13 (0.02)
Heart 0.14 (0.04) 0.12 (0.06) 0.15 (0.03) 0.09 (0.01)
Kidney 20.99 (2.28) 7.02 (1.80) 18.00 (3.02) 6.34 (1.49)
Lung 0.24 (0.05) 0.19 (0.03) 0.24 (0.10) 0.17 (0.05)
Spleen 0.11 (0.02) 0.09 (0.04) 0.11 (0.02) 0.08 (0.02)
Stomach 0.08 (0.05) 0.08 (0.02) 0.07 (0.01) 0.08 (0.06)
Sm. Int. 0.69 (0.12) 0.70 (0.17) 0.71 (0.08) 0.71 (0.16)
Lg. Int. 0.09 (0.07) 0.08 (0.03) 0.09 (0.00) 0.07 (0.02)
Muscle 0.17 (0.07) 0.12 (0.06) 0.15 (0.05) 0.07 (0.02)
Target thigh 0.57 (0.03) 0.49 (0.07) 0.39 (0.04) 0.25 (0.05)
Normal thigli 0.22 (0.04) 0.18 (0.06) 0.21 (0.04) 0,11 (0.02)
Blood 0.18 (0.08) 0.15 (0.05) 0.18 (0.06) 0.11 (0.03)

Data are percentage injected dose per gram (mean of n = 4, with SD in parentheses).