. 2013 Oct 15;188(8):941–947. doi: 10.1164/rccm.201302-0263OC

TABLE 2.

HERITABILITY ESTIMATES

Phenotypes	NHW		AA		Wald P Value^*
Phenotypes	N	Heritability (SE)	N	Heritability (SE)	Wald P Value^*
FEV₁, % predicted^†	6,128	38.4% (5.7%)^‡	2,756	50.9% (13.5%)^‡	0.395
FEV₁/FVC^†	6,128	37.3% (5.7%)^‡	2,756	46.6% (13.9%)^‡	0.538
Log of % emphysema	5,777	28.2% (6.0%)^‡	2,514	31.3% (14.5%)^‡	0.849
Log of % gas trapping	5,385	24.0% (6.4%)^‡	2,192	27.9% (14.9%)^‡	0.808
COPD disease status^†	4,929	37.7% (7.4%)^‡	2,152	37.9% (20.4%)	0.992
Body mass index	6,145	18.7% (6.0%)	2,792	29.0% (12.8%)	0.469
Height	6,145	59.4% (5.6%)^‡	2,792	45.5% (13.5%)^‡	0.341

Definition of abbreviations: AA = African American; COPD = chronic obstructive pulmonary disease; NHW = non-Hispanic white.

Wald test for the comparison of heritability estimation between NHW and AA.

^{^†}

After ascertainment adjustment, heritability of FEV₁ is still 38.4% and FEV₁/FVC is 37.0% in NHW. In the AA population the adjusted heritability of FEV₁ is 51.0% and FEV₁/FVC is 49.4%.

^{^‡}

LRT P value for testing heritability different from zero passed threshold 0.05.