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. 2013 Oct 24;174(3):364–371. doi: 10.1111/cei.12193

Fig. 3.

Fig. 3

Eight weeks of anti-CD40L treatment suppresses CD4+ and CD8 T+ cell activation. (a) Absolute number of intrahepatic immune cell subpopulations. (b) Frequency of naive (CD44−CD62L+), effector (CD44+CD62L−), and memory (CD44+CD62L+) subpopulations in CD4+ and CD8+ T cell subsets in spleen and liver. (c) CD69+ and (d) interferon (IFN)-γ-expressing cell in intrahepatic CD4+ and CD8+ T cells in anti-CD40L and immunoglobulin (Ig)G (control)-treated mice. Data are expressed as the mean ± standard error of the mean. *P < 0·05; two-tailed unpaired Mann–Whitney U-test.