Figure 2.

Effects of N-acetylcysteine (NAC) and/or iron (Fe) short-term administration on serum aspartate transaminase (AST) (a) and alanine transaminase (ALT) (b) levels in rats subjected to ischemia-reperfusion (IR). Animals were treated as shown in Figure 1. Data are expressed as means ± SEM for 3 to 9 animals per group. Significance studies (P < 0.05; one-way ANOVA and Newman-Keuls' test) are indicated by the letters identifying each experimental group. Inset: net changes in serum AST and ALT levels induced by IR correspond to the differences between groups (b-a) (controls), (d-c) (Fe), (f-e) (NAC), and (h-g) (NAC + Fe).