(a)
| Hematologic adverse events | Number of events (possibly multiple events from same participant) | Number of participants experiencing (multiple) events | Number of participants (with most severe event if there are multiple) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total | Grade 1 | Grade 2 | Grade 3 | Grade 4 | ||
| Lymphopenia | 42 | 105 | 51 | 2 | 200 | 34 | 15 | 17 | 2 | |
| Anemia | 85 | 61 | 12 | 158 | 41 | 13 | 22 | 6 | ||
| Leukopenia (Total WBC) |
83 | 50 | 16 | 149 | 30 | 8 | 12 | 10 | ||
| Thrombocytopenia | 78 | 13 | 7 | 2 | 100 | 29 | 20 | 4 | 3 | 2 |
| Neutropenia (ANC/AGC) | 41 | 39 | 18 | 1 | 99 | 26 | 4 | 11 | 10 | 1 |
| Total hematologic AEs | 329 | 268 | 104 | 5 | 706 | |||||