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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Pediatr Infect Dis J. 2013 Apr;32(4):10.1097/INF.0b013e31827f44ee. doi: 10.1097/INF.0b013e31827f44ee

Table 3.

Factors associated with detection of NVP resistance in infants HIV-infected between 6 weeks and 6 months of age.*

Factor N (%) Relative Risk
(95 %CI [IQR])
P-value
ARV exposure from study NVP arm 6/8 (75.0 %) 12.8 (1.8 – 89.0) 0.001
regimen Placebo arm 1/17 (5.9 %)

ARV exposure for PMTCT Maternal ZDV prophylaxis: 0.5 (0.2 – 1.8) 0.355
Yes 4/18 (22.2 %)
No 3/7 (42.9 %)

Maternal 3TC prophylaxis: 0.4 (0.1 – 2.9) 0.626
Yes 1/7 (5.9 %)
No 6/18 (75.0 %)

Infant ZDV prophylaxis: 2.3 (0.3 – 16.1) 0.626
Yes 6/18 (33.3 %)
No 1/7 (14.3 %)

ARV exposure for maternal or infant treatment Maternal HAART by 6 months postpartum 7.0 (2.5 – 20.0) 0.003
Yes 4/4 (100.0 %)
No 3/21 (14.2 %)

Infant HAART by 6 months of age -- 1.000
Yes 0/2 (0.0 %)
No 7/23 (30.4 %)

Other factors HIV-infected by 3 months 0.4 (0.1 – 3.0) 0.626
Yes 1/7 (14.3 %)
No 6/18 (75.0 %)
HIV subtype 1.9 (0.3 – 12.8) 0.637
C 6/19 (31.6 %)
A 1/6 (16.7 %)