Table 3.
Factor | N (%) | Relative Risk (95 %CI [IQR]) |
P-value | |
---|---|---|---|---|
ARV exposure from study | NVP arm | 6/8 (75.0 %) | 12.8 (1.8 – 89.0) | 0.001 |
regimen | Placebo arm | 1/17 (5.9 %) | ||
ARV exposure for PMTCT | Maternal ZDV prophylaxis: | 0.5 (0.2 – 1.8) | 0.355 | |
Yes | 4/18 (22.2 %) | |||
No | 3/7 (42.9 %) | |||
Maternal 3TC prophylaxis: | 0.4 (0.1 – 2.9) | 0.626 | ||
Yes | 1/7 (5.9 %) | |||
No | 6/18 (75.0 %) | |||
Infant ZDV prophylaxis: | 2.3 (0.3 – 16.1) | 0.626 | ||
Yes | 6/18 (33.3 %) | |||
No | 1/7 (14.3 %) | |||
ARV exposure for maternal or infant treatment | Maternal HAART by 6 months postpartum | 7.0 (2.5 – 20.0) | 0.003 | |
Yes | 4/4 (100.0 %) | |||
No | 3/21 (14.2 %) | |||
Infant HAART by 6 months of age | -- | 1.000 | ||
Yes | 0/2 (0.0 %) | |||
No | 7/23 (30.4 %) | |||
Other factors | HIV-infected by 3 months | 0.4 (0.1 – 3.0) | 0.626 | |
Yes | 1/7 (14.3 %) | |||
No | 6/18 (75.0 %) | |||
HIV subtype | 1.9 (0.3 – 12.8) | 0.637 | ||
C | 6/19 (31.6 %) | |||
A | 1/6 (16.7 %) |