Table 3.
CD14 SNP | European Americans | African Americans | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Haplotype | rs778584 | rs4914 | rs5744455 | rs5744451 | Freq | Beta (SE) | P-value | Freq | Beta (SE) | P-value |
H1 | C | C | G | A | 0.17 | Referent | --- | 0.44 | Referent | -- |
H2 | T | C | G | A | 0.49 | 67 (11) | 6.15e-08 | 0.31 | 51 (25) | 0.04 |
H3 | C | G | G | A | 0.12 | 87 (15) | 3.23e-08 | 0.07 | 26 (44) | 0.55 |
H4 | C | C | A | A | 0.21 | −46 (12) | 0.0002 | 0.08 | −93 (40) | 0.02 |
H5 | C | C | G | C | <.01 | NA | NA | 0.09 | −262 (37) | 3.2e-013 |
SE = standard error
The global P-value for CD14 haplotype association with sCD14 in EA = 6.65e-31
The global P-value for CD14 haplotype association with sCD14 in AA = 1.28e-12