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. 2013 Oct 26;14:736. doi: 10.1186/1471-2164-14-736

Table 1.

Demographic data in relation to age of the training cohort HCC patients undergoing surgical resection

  All patients
Age ≦40
Age >40
p*
(n = 61) (n = 23) (n = 38)
Patient demographics
Age (years) (median; 25 and 75 percentiles) (range)
47.5; 36.5-60.2 (26-75.7)
35.5; 30.8-37.0 (26-39.5)
56.8; 50.6-64.3 (40.8-75.7)
<0.001
Sex (M:F)
54:7
19:4
35:3
0.409
Albumin (g/dL) (median; 25 and 75 percentiles)
4.0; 3.8-4.4
4.2; 3.9-4.4
4.0; 3.7-4.3
0.129
Total bilirubin (mg/dL) (median; 25 and 75 percentiles)
0.80; 0.6-1.2
0.7; 0.5-1.1
0.9; 0.6-1.2
0.688
ALT (U/L) (median; 25 and 75 percentiles)
41.0; 30.5-57.0
46.0; 35.0-61.0
38.0; 29.8-57.0
0.946
AST (U/L) (median; 25 and 75 percentiles)
40.0; 27.0-66.0
42.0; 27.0-65.0
39.5; 27.0-67.5
0.871
Platelet (/mm3) (median; 25 and 75 percentiles)
182000; 139000-224500
204000; 171000-264000
167000; 131750-2017250
0.087
ICG-15R (%) (retention rate) (median; 25 and 75 percentiles)
8; 5.3-12.8
6; 4-8
10; 6-14.3
0.0055
Child-Pugh A/B (%)
59/2 (96.7%/3.3%)
22/1 (95.7%/4.4%)
37/1 (97.4%/2.6%)
1.000
Tumor characteristics
Tumor size (cm) (median; 25 and 75 percentiles)
4.8; 3.4-8.7
5.0; 4.0-11.0
4.4; 3.2-6.4
0.523
Multinodularity (%)
28 (45.9%)
9 (39.1%)
19 (50.0%)
0.440
AFP (ng/ml) (median; 25 and 75 percentiles)
190; 15-1541
316; 18.4-5499
169.5; 12.9-728.5
0.742
Macroscopic venous invasion (%)
18 (29.5%)
14 (60.9%)
4 (10.5%)
<0.001
Daughter nodule (%)
32 (62.8%)
11 (55.0%)
21 (67.7%)
0.389
Histopathological findings
Cirrhosis in non-tumor part (yes/no) (%)
33/28 (54.1%/45.9%)
4/19 (17.4%/82.6%)
24/14 (63.2%/36.8%)
<0.001
Edmondson grading (I or II/ III or IV) (%)
33/24 (57.9%/42.1%)
11/12 (47.8%/52.2%)
22/12 (64.7%/35.3%)
0.276
Microscopic venous invasion (%) 43 (70.5%) 17 (73.9%) 26 (68.4%) 0.775

ICG-15R: indocyanine green retention rate at 15 minutes;

*p value: comparison between younger and elderly HCC patients.