Table 2.
ESC genes overexpressed in yHCC patients (q < 0.05, Young HCC vs. elder HCC)
| Probe set ID | UniGene ID | Gene title | Gene symbol | Location | Folds |
|---|---|---|---|---|---|
| 219010_at |
Hs.518997 |
chromosome 1 open reading frame 10 |
C1orf106 |
chr1q32.1 |
3.05 |
| 202715_at |
Hs.377010 |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
CAD |
chr2p22-p21 |
1.68 |
| 1555772_a_at |
Hs.437705 |
cell division cycle 25 homolog A (S. pombe) |
*CDC25A |
chr3p21 |
1.89 |
| 226980_at |
Hs.482233 |
DEP domain containing 1B |
DEPDC1B |
chr5q12.1 |
2.08 |
| 201697_s_at |
Hs.202672 |
DNA (cytosine-5-)-methyltransferase 1 |
*DNMT1 |
chr19p13.2 |
1.74 |
| 229115_at |
Hs.649497 |
dynein, cytoplasmic 1, heavy chain 1 |
*DYNC1H1 |
chr14q32.3-qter |
1.78 |
| 200005_at |
Hs.55682 |
eukaryotic translation initiation factor 3, subunit D |
EIF3D |
chr22q13.1 |
1.55 |
| 1554576_a_at |
Hs.434059 |
ets variant gene 4 (E1A enhancer binding protein, E1AF) |
ETV4 |
chr17q21 |
2.02 |
| 220060_s_at |
family with sequence similarity 222, member B |
FAM222B |
chr17q11.2 |
1.56 |
|
| 213008_at |
Hs.513126 |
Fanconi anemia, complementation group I |
*FANCI |
chr15q26.1 |
1.78 |
| 219390_at |
Hs.571333 |
FK506 binding protein 14, 22 kDa |
FKBP14 |
chr7p15.1 |
1.72 |
| 223079_s_at |
Hs.116448 |
glutaminase |
GLS |
chr2q32-q34 |
2.26 |
| 215942_s_at |
Hs.386189 |
G-2 and S-phase expressed 1 |
*GTSE1 |
chr22q13.2-q13.3 |
1.94 |
| 242890_at |
Hs.655830 |
Helicase, lymphoid-specific |
*HELLS |
chr10q24.2 |
2.47 |
| 212966_at |
Hs.632767 |
hypermethylated in cancer 2 |
*HIC2 |
chr22q11.21 |
2.71 |
| 208930_s_at |
Hs.465885 |
interleukin enhancer binding factor 3, 90 kDa |
*ILF3 |
chr19p13.2 |
2.32 |
| 208974_x_at |
Hs.532793 |
karyopherin (importin) beta 1 |
KPNB1 |
chr17q21.32 |
1.82 |
| 202726_at |
Hs.1770 |
ligase I, DNA, ATP-dependent |
*LIG1 |
chr19q13.2-q13.3 |
1.82 |
| 65588_at |
Hs.400876 |
lncRNA LOC388796 |
LOC388796 |
65588_at |
1.68 |
| 224473_x_at |
Hs.523221 |
leucine zipper, putative tumor suppressor 2 |
*LZTS2 |
chr10q24 |
1.61 |
| 64432_at |
Hs.333120 |
MAPKAPK5 antisense RNA 1 |
MAPKAPK5-AS1 |
chr12q24.12 |
1.61 |
| 242260_at |
Hs.268939 |
Matrin 3 |
MATR3 |
chr5q31.2 |
2.35 |
| 235409_at |
Hs.187569 |
MAX gene associated |
MGA |
chr15q14 |
1.79 |
| 228097_at |
Hs.484738 |
myosin regulatory light chain interacting protein |
MYLIP |
chr6p23-p22.3 |
1.64 |
| 208752_x_at |
Hs.524599 |
nucleosome assembly protein 1-like 1 |
NAP1L1 |
chr12q21.2 |
1.66 |
| 214107_x_at |
Hs.740414 |
aminopeptidase puromycin sensitive |
NPEPPS |
chr17q21 |
1.85 |
| 200057_s_at |
Hs.533282 |
non-POU domain containing, octamer-binding |
*NONO |
chrXq13.1 |
1.52 |
| 228566_at |
Hs.464912 |
Cyclin-dependent kinase 2B-inhibitor-related protein |
P15RS |
chr18q12.2 |
1.51 |
| 203103_s_at |
Hs.502705 |
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) |
*PRPF19 |
chr11q12.2 |
1.49 |
| 1555630_a_at |
Hs.301853 |
RAB34, member RAS oncogene family |
RAB34 |
chr17q11.2 |
3.14 |
| 206499_s_at |
Hs.469723 |
regulator of chromosome condensation 1 |
*RCC1 |
chr1p36.1 |
1.59 |
| 200858_s_at |
Hs.512675 |
ribosomal protein S8 |
RPS8 |
chr1p34.1-p32 |
1.36 |
| 209127_s_at |
Hs.584842 |
squamous cell carcinoma antigen recognized by T cells 3 |
SART3 |
chr12q24.1 |
2.03 |
| 214728_x_at |
Hs.327527 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, a4 |
*SMARCA4 |
chr19p13.2 |
1.61 |
| 201072_s_at |
Hs.476179 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, c1 |
SMARCC1 |
chr3p23-p21 |
1.89 |
| 228990_at |
Hs.632377 |
small nucleolar RNA host gene 12 (non-protein coding) |
SNHG12 |
chr1p35.3 |
1.86 |
| 218324_s_at |
Hs.654826 |
spermatogenesis associated, serine-rich 2 |
SPATS2 |
chr12q13.12 |
1.84 |
| 202826_at |
Hs.233950 |
serine peptidase inhibitor, Kunitz type 1 |
SPINT1 (HAI-1) |
chr15q15.1 |
3.36 |
| 200956_s_at |
Hs.523680 |
structure specific recognition protein 1 |
*SSRP1 |
chr11q12 |
1.78 |
| 207627_s_at |
Hs.48849 |
transcription factor CP2 |
TFCP2 |
chr12q13 |
1.66 |
| 212770_at |
Hs.709205 |
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) |
TLE3 |
chr15q22 |
1.51 |
| 208837_at |
Hs.513058 |
transmembrane emp24 protein transport domain containing 3 |
TMED3 |
chr15q24-q25 |
2.77 |
| 238797_at |
Hs.13543 |
tripartite motif-containing 11 |
TRIM11 |
chr1q42.13 |
1.51 |
| 235476_at |
Hs.212957 |
tripartite motif-containing 59 |
TRIM59 |
chr3q26.1 |
2.00 |
| 209053_s_at |
Hs.113876 |
Wolf-Hirschhorn syndrome candidate 1 |
WHSC1 |
chr4p16.3 |
1.97 |
| 204799_at |
Hs.475208 |
zinc finger, BED-type containing 4 |
ZBED4 |
chr22q13.33 |
1.72 |
| 228988_at | Hs.326801 | zinc finger protein 711 | ZNF711 | chrXq21.1-q21.2 | 3.40 |
*Genes discussed in the text.